Guidelines / Publications
Legend
Asthma
FeNO

Provocholine
Objective Testing (All Three Products)
Guidelines
Guidelines
| Asthma: diagnosis, monitoring and chronic asthma management, NICE 2021 | |
| British guideline on the management of asthma, BTS 2019 | |
| European Respiratory Society Guidelines for the Diagnosis of Asthma in Adults, Louis 2022 | |
| European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years, Gaillard 2021 | |
| Global Strategy for Asthma Management and Prevention, GINA 2022 | |
| Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline, Holguin 2020 | |
| Expert panel report 3 (EPR-3): guidelines for the diagnosis and management of asthma: summary report 2007. National Asthma Education and Prevention Program, 2007 | |
| Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline, Khatri 2021 | |
| An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FeNO) for clinical applications, Dweik, 2011 | |
| Guidelines for Methacholine and Exercise Challenge Testing-1999. Crapo,2000 | |
| ERS Guidelines for the management of work-related asthma. Baur, 2012 | |
| An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction. Parsons, 2013 |
Technical Standards
| ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing, Hallstrand 2018 | |
| A European Respiratory Society technical standard: exhaled biomarkers in lung disease, Horvath, 2017 |
Publications
Diagnosing Asthma
Reevaluation of diagnosis in adults with physician-diagnosed asthma, Aaron 2017
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| Underdiagnosis and Overdiagnosis of Asthma, Aaron 2018 | |
| (Correcting) misdiagnoses of asthma: a cost effectiveness analysis, Pakhale 2011 | |
| Misdiagnosis of Asthma in Schoolchildren, Yang 2017 | |
| Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Louis 2020 | |
| The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management, Wang 2017 | |
| Effectiveness of FeNO-guided treatment in adult asthma patients: A systematic review and meta-analysis, Korevaar 2023 | |
| Use of exhaled nitric oxide measurements to guide treatment in chronic asthma, Smith 2005 |
Diagnosing EIB
| FeNO and Exercise Testing in Children at Risk of Asthma. Schoos, 2017 |
Bronchial Challenge Testing/FeNO in Children
| Methacholine challenge testing is superior to the exercise challenge for detecting asthma in children, Zaczeniuk 2015 | |
| Predictive Factors for a Shortened Methacholine Challenge Protocol in Children, Proulx 2020 | |
| | Exhaled Nitric Oxide in Childhood Allergic Asthma Management A Randomised Controlled Trial. Peirsman, 2013 |
| | Inflammatory in pediatric asthma: A review of fractional exhaled nitric oxide in clinical practice. |
Safety and Efficacy
| Methacholine bronchial provocation test for assessment of bronchial hyperresponsiveness in preschool children, Li 2019 | |
| Bronchial Provocation with Methacholine: Literature Review on Safety, TechEd 2010 |
Assessing Occupational Asthma (Military, Police Forces and Fire Fighters)
| Baseline Spirometry as a Predictor of Positive Methacholine Challenge Testing for Exertional Dyspnea, Hunninghake 2022 | |
| Progress in Occupational Asthma,Tiotiu AL, 2020 | |
| Asthma tests in the assessment of military conscripts, Miedinger 2010 | |
| Diagnostic Tests for Asthma in Firefighters, Miedinger 2007 | |
| Lemiere C, NGuyen S, Sava F, D’Alpaos V, Huaux F, Vandenplas O. Occupational asthma phenotypes identified by increased fractional exhaled nitric oxide after exposure to causal agents, Lemiere,2014 | |
| Martini A, Sbardella D, Bertini L, Capanna S, Spalletta M, D’Ovidio MC. Airway inflammation in professional divers: FeNO as a marker, Martini, 2012 |
Economic Impacts
Cost-effectiveness of implementing objective diagnostic verification of asthma in the United States, Yaghoubi 2020 | |
(Correcting) misdiagnoses of asthma: a cost effectiveness analysis, Pakhale 2011 | |
Cost-effectiveness and Budget Impact of Routine Use of Fractional Exhaled Nitric Oxide Monitoring for the Management of Adult Asthma Patients in Spain. Sabatelli, 2017 |

Provocholine®

