Guidelines / Publications

Legend

Asthma

FeNO

Provocholine

Objective Testing (All Three Products)

Guidelines

Guidelines

Asthma: diagnosis, monitoring and chronic asthma management, NICE 2021
British guideline on the management of asthma, BTS 2019
European Respiratory Society Guidelines for the Diagnosis of Asthma in Adults, Louis 2022
European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years, Gaillard 2021
Global Strategy for Asthma Management and Prevention, GINA 2022
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline, Holguin 2020
Expert panel report 3 (EPR-3): guidelines for the diagnosis and management of asthma: summary report 2007. National Asthma Education and Prevention Program, 2007
Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline, Khatri 2021 
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FeNO) for clinical applications, Dweik, 2011
Guidelines for Methacholine and Exercise Challenge Testing-1999. Crapo,2000 
ERS Guidelines for the management of work-related asthma. Baur, 2012 
An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction. Parsons, 2013 

 

Technical Standards

ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing, Hallstrand 2018
A European Respiratory Society technical standard: exhaled biomarkers in lung disease, Horvath, 2017

 

Publications

Diagnosing Asthma

Reevaluation of diagnosis in adults with physician-diagnosed asthma, Aaron 2017

 

Underdiagnosis and Overdiagnosis of Asthma, Aaron 2018
(Correcting) misdiagnoses of asthma: a cost effectiveness analysis, Pakhale 2011
Misdiagnosis of Asthma in Schoolchildren, Yang 2017
Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Louis 2020
The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management, Wang 2017
Effectiveness of FeNO-guided treatment in adult asthma patients: A systematic review and meta-analysis, Korevaar 2023
Use of exhaled nitric oxide measurements to guide treatment in chronic asthma, Smith 2005

 

Diagnosing EIB

FeNO and Exercise Testing in Children at Risk of Asthma. Schoos, 2017

Bronchial Challenge Testing/FeNO in Children

Methacholine challenge testing is superior to the exercise challenge for detecting asthma in children, Zaczeniuk 2015
Predictive Factors for a Shortened Methacholine Challenge Protocol in Children, Proulx 2020
Exhaled Nitric Oxide in Childhood Allergic Asthma Management A Randomised Controlled Trial. Peirsman, 2013
Inflammatory in pediatric asthma: A review of fractional exhaled nitric oxide in clinical practice.

 

Safety and Efficacy

Methacholine bronchial provocation test for assessment of bronchial hyperresponsiveness in preschool children, Li 2019
Bronchial Provocation with Methacholine: Literature Review on Safety, TechEd 2010

Assessing Occupational Asthma (Military, Police Forces and Fire Fighters)

Baseline Spirometry as a Predictor of Positive Methacholine Challenge Testing for Exertional Dyspnea, Hunninghake 2022
Progress in Occupational Asthma,Tiotiu AL, 2020
Asthma tests in the assessment of military conscripts, Miedinger 2010
Diagnostic Tests for Asthma in Firefighters, Miedinger 2007
Lemiere C, NGuyen S, Sava F, D’Alpaos V, Huaux F, Vandenplas O. Occupational asthma phenotypes identified by increased fractional exhaled nitric oxide after exposure to causal agents, Lemiere,2014
Martini A, Sbardella D, Bertini L, Capanna S, Spalletta M, D’Ovidio MC. Airway inflammation in professional divers: FeNO as a marker, Martini, 2012

 

Economic Impacts

Cost-effectiveness of implementing objective diagnostic verification of asthma in the United States, Yaghoubi 2020

(Correcting) misdiagnoses of asthma: a cost effectiveness analysis, Pakhale 2011

Cost-effectiveness and Budget Impact of Routine Use of Fractional Exhaled Nitric Oxide Monitoring for the Management of Adult Asthma Patients in Spain. Sabatelli, 2017

 

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