Guidelines / Publications

Legend

Asthma

FeNO

Provocholine

Aridol

Objective Testing (All Three Products)

Guidelines

Guidelines

Asthma: diagnosis, monitoring and chronic asthma management, NICE 2021
British guideline on the management of asthma, BTS 2019
European Respiratory Society Guidelines for the Diagnosis of Asthma in Adults, Louis 2022
European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years, Gaillard 2021
Global Strategy for Asthma Management and Prevention, GINA 2022
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline, Holguin 2020
Expert panel report 3 (EPR-3): guidelines for the diagnosis and management of asthma: summary report 2007. National Asthma Education and Prevention Program, 2007
Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline, Khatri 2021 
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FeNO) for clinical applications, Dweik, 2011
Guidelines for Methacholine and Exercise Challenge Testing-1999. Crapo,2000 
ERS Guidelines for the management of work-related asthma. Baur, 2012 
An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction. Parsons, 2013 

 

Technical Standards

ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests, Coates 2017
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing, Hallstrand 2018
A European Respiratory Society technical standard: exhaled biomarkers in lung disease, Horvath, 2017

 

Publications

Diagnosing Asthma

Reevaluation of diagnosis in adults with physician-diagnosed asthma, Aaron 2017

 

Underdiagnosis and Overdiagnosis of Asthma, Aaron 2018

(Correcting) misdiagnoses of asthma: a cost effectiveness analysis, Pakhale 2011

Misdiagnosis of Asthma in Schoolchildren, Yang 2017

Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Louis 2020

Usefulness of mannitol challenge testing for diagnosing asthma in everyday clinical practice, Pedersen 2020

Inhaled Mannitol in the Diagnosis and the Management of Asthma, Anderson 2016

Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study, Sverrild 2009

IOC Consensus Statement on Asthma in Elite Athletes, Ljungqvist 2008

The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management, Wang 2017

Effectiveness of FeNO-guided treatment in adult asthma patients: A systematic review and meta-analysis, Korevaar 2023

Use of exhaled nitric oxide measurements to guide treatment in chronic asthma, Smith 2005

 

Diagnosing EIB

Exercise-induced bronchoconstriction update, Weiler 2016

Bronchial Provocation testing for the Identification of Exercise-Induced Bronchoconstriction, Brannan 2020

Mannitol dry powder challenge in comparison with exercise testing in children, Barben 2011

Mannitol and Exercise Challenge Tests in Asthmatic Children, Kersten 2009

FeNO and Exercise Testing in Children at Risk of Asthma. Schoos, 2017

Bronchial Challenge Testing/FeNO in Children

Inhaled Mannitol Identifies Methacholine-Responsive Children with Active Asthma, Subbarao 2000

Mannitol and Exercise Challenge Tests in Asthmatic Children, Kersten 2009

Mannitol dry powder challenge in comparison with exercise testing in children, Barben 2011

The Safety and feasibility of the inhaled mannitol challenge test in young children, Alblooshi 2013

 

Methacholine challenge testing is superior to the exercise challenge for detecting asthma in children, Zaczeniuk 2015

Predictive Factors for a Shortened Methacholine Challenge Protocol in Children, Proulx 2020

Exhaled Nitric Oxide in Childhood Allergic Asthma Management A Randomised Controlled Trial. Peirsman, 2013

Inflammatory in pediatric asthma: A review of fractional exhaled nitric oxide in clinical practice.

 

Safety and Efficacy

Methacholine bronchial provocation test for assessment of bronchial hyperresponsiveness in preschool children, Li 2019

Bronchial Provocation with Methacholine: Literature Review on Safety, TechEd 2010

The Safety and feasibility of the inhaled mannitol challenge test in young children, Alblooshi 2013

The Safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness: a phase 3 comparison study with hypertonic (4.5%) saline, Brannan 2005

Assessing Occupational Asthma (Military, Police Forces and Fire Fighters)

Baseline Spirometry as a Predictor of Positive Methacholine Challenge Testing for Exertional Dyspnea, Hunninghake 2022

Progress in Occupational Asthma,Tiotiu AL, 2020

Asthma tests in the assessment of military conscripts, Miedinger 2010

Diagnostic Tests for Asthma in Firefighters, Miedinger 2007

Use of Mannitol (Aridol) Bronchial Provocation Testing, Brennan 2006

The efficacy and safety of mannitol challenge in a workplace setting for assessing asthma prevalence, Menezes 2018

Lemiere C, NGuyen S, Sava F, D’Alpaos V, Huaux F, Vandenplas O. Occupational asthma phenotypes identified by increased fractional exhaled nitric oxide after exposure to causal agents, Lemiere,2014

Martini A, Sbardella D, Bertini L, Capanna S, Spalletta M, D’Ovidio MC. Airway inflammation in professional divers: FeNO as a marker, Martini, 2012

 

Economic Impacts

Cost-effectiveness of implementing objective diagnostic verification of asthma in the United States, Yaghoubi 2020

(Correcting) misdiagnoses of asthma: a cost effectiveness analysis, Pakhale 2011

Cost-effectiveness and Budget Impact of Routine Use of Fractional Exhaled Nitric Oxide Monitoring for the Management of Adult Asthma Patients in Spain. Sabatelli, 2017

 

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